Click here for more information about Algenuity
Click here for more information about Liqofluxphenometrics515R1
Visit cricatalyst.com!Evodos Separation Technology

Money

Venter Institute-led team gets $10.7M for diatom research

October 4, 2017
AlgaeIndustryMagazine.com

Scientists, led by the La Jolla, CA-based J. Craig Venter Institute (JCVI), a not-for-profit genomic research organization, were recently awarded a 5-year, $10.7 million grant by the United States Department of Energy, Office of Science, Biological and Environmental Research (BER), BER Genomic Science Program, to optimize metabolic networks in diatoms – model photosynthetic microalgae. The aim of this work is to substantially increase lipid production, enabling next-generation biofuels and bioproducts.

“Fusing novel, large-scale genome manipulation with metabolic modeling through design-build-test cycles, and detailed physiological characterization represents an exciting leap forward in tailoring organisms for maximum productivity of biofuels and other high value products,” says project principal investigator, Andrew Allen, Ph.D.

Building on prior synthetic biology and diatom research, methodologies will be developed and optimized for introducing and transplanting new biological functions into diatoms, which are a globally abundant class of algae. Initial modeling exercises will guide targeted genetic manipulations, associated systems biology experiments, and result in iterative network and genome-scale cellular modeling.

Optimization of approaches for genome-scale engineering and implementation of reprogrammed biological function, such as replacement of storage carbohydrates with storage lipids, will occur in parallel. Dr. Allen added, “We hope to overcome currently limiting efficiency bottlenecks to promote production of high-value, fuel-related metabolites.”

Based on the photosynthetic efficiency and growth potential of microalgae, it is estimated that annual oil production of greater than 30,000 liters, or about 200 barrels of microalgal oil per hectare of land may be achievable in mass culture of oil-rich algae. This is 100-fold greater than that of soybeans, a major feedstock currently used for biodiesel in the U.S. Genome-scale engineering provides a method for substantially raising this already promising production ceiling.

Project team members also include Chris Dupont, Ph.D., J. Craig Venter Institute; Graham Peers, Ph.D., and Wen Zhou, Ph.D., Colorado State University; Jamey D. Young, Ph.D., Vanderbilt University; and Karsten Zengler, Ph.D., and Bernhard Ø Palsson, Ph.D., University of California, San Diego.

This award was made in response to solicitation DE-FOA-0001650, Biosystems Design to Enable Next-Generation Biofuels and Bioproducts.

Founded by J. Craig Venter, Ph.D., the JCVI not-for-profit research institute is home to approximately 200 scientists and staff with expertise in human and evolutionary biology, genetics, bioinformatics/informatics, information technology, high-throughput DNA sequencing, genomic and environmental policy research, and public education in science and science policy.

More Like This…

HOME A.I.M. Archives

Copyright ©2010-2017 AlgaeIndustryMagazine.com. All rights reserved. Permission required to reprint this article in its entirety. Must include copyright statement and live hyperlinks. Contact editorial@algaeindustrymagazine.com. A.I.M. accepts unsolicited manuscripts for consideration, and takes no responsibility for the validity of claims made in submitted editorial.

twittertopbarlinks_eventstopbarlinks_requesttopbarlinks_archives

From The A.I.M. Archives

— Refresh Page for More Choices
Prior posts highlight the value proposition for building a Green Friendship Bridge of algae microfarms in lieu of 1%, (13 miles) of Donald Trump’s proposed border wall wi...
EPA (eicosapentaenoic acid) fortified eggs are developing quite a demand among middle and upper-class consumers in China. With clinical trials demonstrating that EPA can ...
Judy Siegel-Itzkovich writes in the Jerusalem Post that Dr. Iftach Yacoby and his research team at Tel Aviv University, in Israel, have genetically altered microalgae to ...
Tom Lindfors writes in the New Richmond News about how the Roberts, Wisconsin, wastewater treatment plant – considered a minor utility designed to treat an average flow o...
A Quebec-based company that specializes in the manufacturing and commercialization of marine and seaweed-based products for agriculture and horticulture constructed a new...
The genome of the fuel-producing green microalga Botryococcus braunii has been sequenced by a team of researchers led by a group at Texas A&M AgriLife Research. The r...
Diane Stopyra writes in Salon.com that a growing number of coastal states around the country are undertaking large-scale seaweed farming projects. While farms are underwa...
Marlene Cimons, nexusmedianews.com reports that researchers at the University of California San Diego and Sapphire Energy have successfully grown a genetically engineered...
Algatech has announced the opening of Algatech Inc., a New York City-based subsidiary created to serve the North American market. The company has appointed Ken Seguine to...
The U.S. Department of Energy (DOE) has announced the selection of three projects to receive up to $8 million, aimed at reducing the costs of producing algal biofuels and...
The European Synchrotron Radiation Facility (ESRF) reports that an international team has discovered an enzyme which allows microalgae to convert some of their fatty acid...
The Department of Energy has just announced $22 million in funding through the Advanced Research Projects Agency-Energy (ARPA-E) for 18 innovative projects as part of the...