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The NoMorFilm Project

May 21, 2016

Sara Soto Explains the NoMorFilm project from ISGlobal on Vimeo.

Over 800,000 prosthetic devices – and an even higher number of catheters – are inserted in patients in the European Union every year. Out of these patients, nearly 8% will suffer from a post-implant infection.

The bacteria and fungi found in infected prostheses do not respond to conventional antibiotics; they form a biofilm highly resistant to existing pharmacological treatments. Finding new and effective antimicrobial agents to prevent infections has therefore become a clinical priority, and has resulted in a task force called the NoMorFilm project.

In this video Dr. Sara Soto, coordinator of NoMorFilm, explains the project, which is funded by the European Union Horizon 2020 program. The aim of NoMorFilm is to screen microalgae for new antibiotics with activity against the bacteria and fungi responsible for the infections that occur around prosthetic devices and catheters.

The NoMorFilm project team will begin by analyzing thousands of compounds isolated from microalgae to identify new biomolecules with promising antibacterial properties. These isolated marine molecules will then be tested in animal models to rule out toxicity in humans. Finally, prototype catheters and prostheses incorporating these new biomolecules will be developed.

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