Click here for more information about Algenuity
Click here for more information about Liqofluxphenometrics515R1
Visit cricatalyst.com!Evodos Separation Technology

Research

Study: red seaweed slows cancer growth

February 10, 2017
AlgaeIndustryMagazine.com

Kappaphycus alvarezii, or elkhorn sea moss, is a species of red algae, and one of the most important commercial sources of carrageenans. Photo: courtesy quazoo.com

Mae Chan writes in RiseEarth.com about a recent study in Malaysia that found Kappaphycus alvarezii red seaweed helps in slowing down the growth rate of mammary tumors – which researchers say displays the alga’s potential as a natural aid in cancer treatment.

K. alvarezii is an algae species cultivated for its nutrients and nutraceutical uses in South East Asia. It is an important source of kappa carrageenan, a hydrocolloid used as food additive — acting as a gelling, emulsifying, thickening and stabilizing agent in both pharmaceutical and nutraceutical products.

The red seaweed has significant amounts of protein, vitamins, trace elements and a wide range of second metabolites not found in other organisms. Most importantly, it has antiproliferative properties — or the ability to inhibit cell growth.

To determine if K. alvarezii extract can slow down growth of cancer cells, researchers from the USCI University in Malaysia tested it on rats induced with mammary tumors by using DMBA, a powerful organ-specific laboratory carcinogen.

Twenty rats were divided into three groups: experimental, untreated, and normal, plus control groups. Both experimental and untreated groups received DMBA, with the experimental group receiving K. alvarezii crude extracts orally, and only after tumors developed.

An MTT assay determined if the cancer cells induced in the rats would be able to survive following treatments of various concentrations of K.alvarezii. The concentrations used during the study were 1.0 mg/mL, 3.0 mg/mL, 5.0 mg/mL, 7.0 mg/mL, 9.0 mg/mL, 12.0 mg/mL and 15.0 mg/mL respectively.

Researchers noted that K.alvarezii administered at 1.0mg/mL started inhibiting cell growth, and showed a reduction of cells compared to the solvent control.

“The percentage of cell viability of MCF-7 (breast cancer cells) was reduced from 84.91% to 0.81% which showed a significant reduction of cell viability when the concentration of K. alvarezii extract is increased,” they wrote. “Based on the observation, K. alvarezii extract is able to induce the apoptosis of the MCF-7.”

Read More

More Like This…

Copyright ©2010-2018 AlgaeIndustryMagazine.com. All rights reserved. Permission required to reprint this article in its entirety. Must include copyright statement and live hyperlinks. Contact editorial@algaeindustrymagazine.com. A.I.M. accepts unsolicited manuscripts for consideration, and takes no responsibility for the validity of claims made in submitted editorial.

twittertopbarlinks_eventstopbarlinks_requesttopbarlinks_archives

From The A.I.M. Archives

— Refresh Page for More Choices
WesTech Engineering, Inc. and Utah State University’s Sustainable Waste-to-Bioproducts Engineering Center (SWBEC) are jointly engaged in developing processes for more eff...
Carlsbad-based Surftech, a stand-up paddle (SUP) and Surfboard manufacturing company has announced its collaboration with BLOOM, a materials development company, to devel...
Memory Maninga reports for Zambia Daily Mail that in Mansa, the capital of the Luapula Province of Zambia, spirulina is being grown in ponds in the communities because of...
A Bay Area company has patented a group of three single-celled, algae-like organisms that, when grown together, can produce high quantities of sugar just right for making...
Researchers at ETH Zurich, Empa and the Norwegian research institute SINTEF are pursuing a new approach to treating arthritis. This is based on a polysaccharide, a long-c...
The Department of Energy has just announced $22 million in funding through the Advanced Research Projects Agency-Energy (ARPA-E) for 18 innovative projects as part of the...
The Utah Science Technology and Research (USTAR) initiative, a technology-based economic development program funded by the state of Utah, has awarded a $175,320 grant for...
Cyanotech Corporation a leader in microalgae-based, high-value nutrition and health products, announced financial results for the third quarter and first nine months of f...
Trade Arabia reports that the Oman Centre for Marine Biotechnology (OCMB) recently signed a memorandum of understanding with Swedish Algae Factory to support the domestic...
The Natural Algae Astaxanthin Association (NAXA), headquartered in Spring, Texas, has announced that Chile-based Atacama Bio is its newest executive member. Atacama Bio h...
Israeli-based Algatechnologies, Ltd. (Algatech) has become the major shareholder in Supreme Health New Zealand, Ltd. (Supreme) to supply the rapidly growing markets in Ch...
Israeli-based Algatechnologies, Ltd. (Algatech), is teaming up with the Italian R&D company, Sphera Encapsulation S.r.l (Sphera), to develop innovative functional ingredi...