Click here for more information about Algenuity
Click here for more information about Liqofluxphenometrics515R1
Visit cricatalyst.com!Evodos Separation Technology

Innovations

Microalgal vaccine for farmed fish

September 5, 2017
AlgaeIndustryMagazine.com

(From left) Dr. Padmanabhan Saravanan, domain lead of biological testing at Temasek’s School of Applied Science; Mr Chan Kah Guan, director of industry partnerships; team lead Diana Chan; Dr Lee Chee Wee, director at TP’s School of Applied Science. Photo: Feline Lim

Audrey Tan writes in Singapore’s Straightstimes.com that, when it comes to putting healthy fish on the dinner table, experts believe vaccination is the way to go. But it is a laborious process. Workers at fish farms have to manually inject young fish with the vaccine one by one in order to protect them against specific diseases.

To develop an easier process, scientists at Temasek Polytechnic (TP) are working with an Israeli partner that will allow farmers to mix the vaccine into the fish feed. The oral vaccine against fish iridovirus — a common disease in farmed fish that can kill them — was developed by inserting parts of the iridovirus into a special type of microalgae, which are then mixed with feed and fed to the fish.

For the Temasek Polytechnic scientists, the key to developing the oral microalgal vaccine was finding a substance that could encapsulate the biological compounds in a way that would prevent it from being destroyed by fish stomach acids.

They worked with Israeli biotechnology company TransAlgae to develop a novel algae-based technology that allows for the oral delivery of protein-based drugs, such as vaccines, to animals. This method uses a strain of algae that can withstand acids in the fish’s digestive tract.

Dr. Ofra Chen, vice-president of research and development at TransAlgae Israel, told The Straits Times: “The specific algae cell wall… protects the vaccine from degradation in the animal digestive system and enables its delivery in its intact and functional form.”

While antibiotics are chemical compounds designed to kill bacteria, vaccines are preventive. They contain biological compounds that boost the fish’s own immune system against the virus. Vaccinating fish against specific diseases reduces the need to treat them with antibiotics when they are sick.

When humans consume antibiotics-fed fish, there is the possibility of residual traces of the drug passing through the food chain and ending up in the bellies of humans, which could build up a resistance to antibiotics.

The hope is that this would encourage wider adoption of vaccines here when rolled out commercially by 2021, reducing farmers’ reliance on antibiotics and leading to healthier fish, said team lead Dr. Diana Chan, head of the Centre for Aquaculture and Veterinary Science at Temasek Polytechnic’s School of Applied Science.

A spokesman for the Agri-Food and Veterinary Authority (AVA) said fish vaccines have helped to reduce disease occurrence in farmed fish, and contributed to the sustainable growth of aquaculture in many countries.

She noted several advantages of oral vaccinations for fish. “It is a quick and easy way to vaccinate a large number of fish, causes less stress to the fish, requires less time and effort to administer, and can be given to fish of all sizes, including those too small to be handled for injections,” said the spokesman.

She added that farms should choose the vaccine administration method that suits them best. “For example, farmers can choose to vaccinate smaller fish with oral vaccines and subsequently boost their immunity with repeated doses of the same oral vaccine, or an injectable version of the vaccine.”

Read More

More Like This…

Copyright ©2010-2019 AlgaeIndustryMagazine.com. All rights reserved. Permission required to reprint this article in its entirety. Must include copyright statement and live hyperlinks. Contact editorial@algaeindustrymagazine.com. A.I.M. accepts unsolicited manuscripts for consideration, and takes no responsibility for the validity of claims made in submitted editorial.

twittertopbarlinks_eventstopbarlinks_requesttopbarlinks_archives

From The A.I.M. Archives

— Refresh Page for More Choices
The Utah Science Technology and Research (USTAR) initiative, a technology-based economic development program funded by the state of Utah, has awarded a $175,320 grant for...
“The Israeli food-tech industry has been growing in leaps and bounds in recent years and is taking a leading role worldwide with a broad range of innovative companies and...
Israeli-based Algatechnologies, Ltd. (Algatech) has become the major shareholder in Supreme Health New Zealand, Ltd. (Supreme) to supply the rapidly growing markets in Ch...
French researchers have been exploring the potential of algae for boosting the immune systems of animals and reducing the use of antibiotics in livestock farming. Past st...
JapanNews.com reports that Euglena Co., a Tokyo-based maker of nutritional supplements, is spending ¥5.8 billion ($5.3 million USD) on building a test refinery that conve...
Global EcoPower (GEP), of Aix-en-Provence, France, has signed a 5-year partnership contract with the French Alternative Energies and Atomic Energy Commission (CEA). This ...
Researchers at Los Alamos National Laboratory and partner institutions have provided the first published report of algae using raw plants as a carbon energy source. The r...
Milenio.com reports that BiomiTech, a Mexican company, won a prestigious innovation award for its air purification system at the Contamination Expo Series 2018 held in Bi...
Cécile Barbière writes for Euractive.fr (translated by Rob Kirby) that, in large greenhouses formerly home to the tomatoes and cucumbers of the market gardening Groupe Ol...
The Swiss Algae Consortium Association (SWALG) was founded in May 2018 as a non-profit organization that serves as a platform for algae-related activities in Switzerland ...
E.A. Crunden writes in thinkprogress.org that Florida’s first gubernatorial debate was dominated by environmental and climate issues, with an emphasis on the state’s alga...
Jason Huffman writes in UndercurrentNews.com that the Kampachi Company, a mariculture business focused on expanding the environmentally sound production of sashimi-grade ...