Click here for more information about Algenuity
Click here for more information about LiqofluxPhenometrics Buy 3 Get 1 Free
Visit cricatalyst.com!Evodos Separation Technology

Innovations

Magnetized microalgae could be the future of medicine

January 15, 2019
AlgaeIndustryMagazine.com

Scientists develop magnetized microalgae microswimmers using terbium.
Courtesy: AdvancedScienceNews.com

J dropcapessica D’Lima writes in AdvancedScienceNews.com that medicine is moving towards minimally invasive procedures, which have important patient-oriented benefits such as shorter hospitalization durations and lower risks for infections and complications. In this regard, microrobots have emerged as a promising medical tool due to their potential to reach tissues and body cavities that are hard to navigate into, and with far-reaching applications such as imaging, targeted therapy, and tissue engineering. However, the miniaturization of biomedical tools comes with certain challenges: precise actuation, motion control, and safety.

Swimming microorganisms are useful biomedical tools due to their self‐powered movement and controllable steering properties, based on biological propulsion and sensing. Thus far, mainly (magnetotactic) bacteria have been investigated, but they can be harmful for humans and biocompatibility tests are still lacking. Furthermore, bacteria require special culture conditions to maintain their stability, which might limit their biomedical applications.

A possible alternative to bacteria as microrobotic devices are microalgae, such as Chlamydomonas reinhardtii, which are easy to culture. However, these fast swimming cells are not magnetic and thus not steerable in the human body. In previous studies, microalgae have been magnetized by attaching magnetic nanocrystals onto them. The disadvantage of this approach is that the nanocrystals hamper the movement of the cells, preventing drugs from being easily attached onto them.

To this effect, a team of scientists has shown that microalgae can gain magnetotactic behavior by simply incorporating a magnetic element, the rare earth element terbium. Once the algae incorporate terbium ions, they demonstrate superparamagnetic behavior with magnetic moments comparable to those of magnetotactic bacteria. These magnetized microalgae can align themselves along an applied magnetic field, which guides them to swim in a directional motion. Biocompatibility tests with human and mouse cells show that these magnetized microalgae are not harmful and could be used as biohybrid microrobots. Furthermore, since the incorporated terbium is luminescent, the magnetotactic microalgae are easy to track in the human body.

Read More

More Like This…

Copyright ©2010-2019 AlgaeIndustryMagazine.com. All rights reserved. Permission required to reprint this article in its entirety. Must include copyright statement and live hyperlinks. Contact editorial@algaeindustrymagazine.com. A.I.M. accepts unsolicited manuscripts for consideration, and takes no responsibility for the validity of claims made in submitted editorial.

twittertopbarlinks_eventstopbarlinks_requesttopbarlinks_archives

From The A.I.M. Archives

— Refresh Page for More Choices
Cécile Barbière writes for Euractive.fr (translated by Rob Kirby) that, in large greenhouses formerly home to the tomatoes and cucumbers of the market gardening Groupe Ol...
Cyanotech Corporation, a Kailua Kona, Hawaii-based leader in high-value nutrition and health products made from algae, has announced financial results for the first quart...
Laura Sanders reports in Sciencenews.org that using algae as local oxygen factories in the brain might one day lead to therapies for strokes or other damage from too litt...
Environmental Technology magazine notes that the difficulty in predicting how algae blooms will develop lies in their variform nature. With a multitude of different bloom...
Amy Thompson writes in Space.com that SpaceX successfully launched its 15th Space Station cargo-resupply mission on Friday, June 29; carrying a payload of experiments des...
Paris-based Solabia Group (“Solabia”) has acquired Algatech Ltd., a global leader in the development, cultivation and commercialization of ingredients delivered from micr...
Jason Huffman writes in UndercurrentNews.com that the Kampachi Company, a mariculture business focused on expanding the environmentally sound production of sashimi-grade ...
Tavelmout Biofarm (TVMB), a Bruneian subsidiary of Tabérumo Corporation — a pioneer in the large-scale cultivation of spirulina using photobioreactors — has launched thei...
San Diego, CA and Kailua-Kona, HI-based Cellana, Inc. has signed an Asset Purchase Agreement with Cyanotech Corporation for the sale of Cellana’s six-acre production and ...
Nature.com reports that swimming algae have been enlisted to carry drugs to individual cells, raising the prospect that such “microswimmers” could deliver targeted therap...
The Swiss Algae Consortium Association (SWALG) was founded in May 2018 as a non-profit organization that serves as a platform for algae-related activities in Switzerland ...
Gerard de Souza reports for the Hindustan Times that researchers at the CSIR-National Institute of Oceanography Goa (India) have found a cleaner, cheaper method to grow b...