go to http://www.aocs.org! Algaetech International — The Future is NowComplete Algae Monitoring System Visit  cricatalyst.com!Nexus — Leaders in Greenhouse Systems Integration

Research

Brown algae’s antioxidant properties investigated

September 12, 2013
AlgaeIndustryMagazine.com

Ectocarpus siliculosus growing on the marine plant Zostera  © Akira Peters, Station Biologique Roscoff

Ectocarpus siliculosus growing on the marine plant Zostera
© Akira Peters, Station Biologique Roscoff

Brown algae contain phlorotannins, aromatic (phenolic) compounds that are unique in the plant kingdom. As natural antioxidants, phlorotannins are of great interest for the treament and prevention of cancer and inflammatory, cardiovascular and neurodegenerative diseases.

Researchers at France’s Végétaux marins et biomolécules (CNRS/UPMC) laboratory at the Station biologique de Roscoff, in collaboration with two colleagues at the Laboratoire des sciences de l’Environnement MARin (Laboratory of Marine Environment Sciences) in Brest (CNRS/UBO/IFREMER/IRD) have recently described the key step in the production of these compounds in Ectocarpus siliculosus, a small brown alga model species. The study also revealed the specific mechanism of an enzyme that synthesizes phenolic compounds with commercial applications.

These findings have been patented and should make it easier to produce the phlorotannins presently used as natural extracts in the pharmaceutical and cosmetic industries. The results have also been published online on the site of the journal The Plant Cell (“Structure/Function Analysis of a Type III Polyketide Synthase in the Brown Alga Ectocarpus siliculosus Reveals a Biochemical Pathway in Phlorotannin Monomer Biosynthesis”).

Until now, extracting phlorotannins from brown algae for use in industry was a complex process, and the biosynthesis pathways of these compounds were unknown. By studying the first genome sequenced from a brown alga, the team in Roscoff identified several genes homologous to those involved in phenolic compound biosynthesis in terrestrial plants.

Among these genes, the researchers found that at least one was directly involved in the synthesis of phlorotannins in brown algae. They then inserted these genes into a bacterium, which thus produced a large quantity of the enzymes that could synthesize the desired phenolic compounds.

One of these enzymes, a type III polyketide synthase (PKS III), was studied in detail and revealed how it produces phenolic compounds. PKS III is able, for example, to synthesize phloroglucinol (notably used in antispasmodic drugs and in explosives) and other phenolic compounds with commercial applications.

Besides this mechanism, results revealed that the compounds had other biological functions in the acclimation and adaptation of brown algae to salinity stress. Knowledge of these biosynthesis pathways would allow researchers to uncover the signaling mechanisms that regulate this metabolism. It would also be useful for understanding the biological and ecological functions of these compounds in other brown algae that are already used commercially.

Read More

More Like This…

HOME Algae Industry Jobs

Copyright ©2010-2013 AlgaeIndustryMagazine.com. All rights reserved. Permission required to reprint this article in its entirety. Must include copyright statement and live hyperlinks. Contact editorial@algaeindustrymagazine.com. A.I.M. accepts unsolicited manuscripts for consideration, and takes no responsibility for the validity of claims made in submitted editorial.

From The A.I.M. Archives

— Refresh Page for More Choices
Natural carotenoid specialists Piveg Inc., with production facilities based in Celaya, Central Mexico, has announced immediate availability of natural astaxanthin materia...
University of Adelaide researchers are using nanotechnology and the fossils of diatoms to develop a novel chemical-free and resistance-free way of protecting stored grain...
Technical standards define critical terms and metrics to add wisdom for the algae industry. Agreement among science and business leaders represents possibly the most diff...
Algatechnologies (“Algatech”), Israel, has announced a more than 100% expansion of its production capacity of AstaPure® brand natural astaxanthin. This doubling of capaci...
Algenist®, Solazyme’s anti-aging skincare brand featuring microalgae, has announced its launch in Nordstrom locations throughout the United States. The launch into Nordst...
Algal oil represents one of the significant segments within the omega-3 polyunsaturated fatty acid (PUFA) ingredients market. Specifically, docosahexaenoic acid (DHA) is ...
Although the use of whole microalgae in animal diets has long been studied, the 
de-fatted biomass of microalgal species, derived from biofuel production research, has on...
By sending algae into space, a U.S. Department of Agriculture (USDA) scientist and his team will be able to study some of the key mechanisms that control plant growth and...
The Algae Biomass Organization (ABO) released the following statement calling on the EPA to include Carbon Capture and Utilization strategies in rules proposed June 2, 20...
A new, outdoor system at the University of Dayton Research Institute has been producing a high volume of algae since its installation in the summer of 2013, even through ...
Four years after the first optimistic calculations, the experimental cultivation of algae at Wageningen University in the Netherlands appears to be meeting expectations. ...
The Guardian reports that Prince Edward Island (P.E.I.), Canada-based Solarvest has created an inventive system utilizing a specific algal strain to grow and produce EPA ...
Jamie Radford writes in the Illawarra Mercury that Pia Winberg, from the University of Wollongong, believes that the South Coast of New South Wales, Australia (NSW) is in...
Kyae Mone Win reports in the Myanmar Times that spirulina has been harvested from Twin Daung lake in Sagaing’s Bu Ta Lin township for over a decade, but climate change an...
Starting in the early 70s, agencies in the former USSR invested more than 20,000 person-years of research and development to produce Bio-Algae Concentrates (BAC) that hel...
Algae manufacturer Cyanotech Corporation has announced implementing three major initiatives to improve Astaxanthin production at their Kailua Kona, Hawaii-based cultivati...
Biofuels derived from the oils produced by algae may offer a low-cost sustainable alternative to fossil fuels. To achieve this goal, optimization of cost effective strate...
Perth, Western Australia-based Algae.Tec Limited has announced that the Reliance Group has converted the first tranche of options following the positive progress achieved...