Click here for more information about Algenuity
Click here for more information about Liqofluxphenometrics515R1
Visit cricatalyst.com!Evodos Separation Technology

Innovations

Algae could prevent limb amputation

March 25, 2019
AlgaeIndustryMagazine.com

Alginate from the cell walls of brown algae was used to form the capsules.
Image: British Heart Foundation

Pranjal Mehar writes in techexplorist.com that a new algae-based treatment could prevent limb amputation for patients with Critical Limb Ischemia.

Critical Limb Ischemia (CLI) is a severe obstruction of the arteries which markedly reduces blood flow to the extremities (hands, feet and legs) and has progressed to the point of severe pain and even skin ulcers or sores.

Clinical trials of cell therapy to date have only shown a modest benefit with disappointing results attributed to the lack of potency of cells injected, including a functional impairment of autologous cells harvested from patients with multiple co-morbidities.

Now, scientists at the St Thomas’ Hospital and King’s College London have developed small capsules using brown algae that contain macrophages, a type of white blood cell. According to scientists, this new algae-based treatment could reduce the need for amputation in people with CLI.

Scientists conducted the trails in mice. Alginate from the cell walls of brown algae, which is mainly found in cold waters in the Northern Hemisphere, was used to form the capsules. They found that these macrophages successfully remained in the injured area, new blood vessels formed, and as a result, more blood reached the damaged area.

Scientists are further planning to move this research into human clinical trials to help the people visiting the hospital with CLI. Scientists believe that this new way of delivering cells could be the key to creating an effective treatment for people suffering from CLI.

Professor Metin Avkiran, Associate Medical Director at the British Heart Foundation which funded the research said, “Our researchers are proving (algae) could hold the key to a new treatment for one of the leading causes of limb amputation. Losing a limb is an all too devastating reality for many patients with CLI. The condition is caused by blockages in arteries that supply blood to the legs and feet, and is triggered by the same process that blocks coronary arteries when someone has a heart attack.”

“This research brings us a step closer to finding treatments for the thousands of people affected by this disabling condition.”

The study has been published in the journal npj Regenerative Medicine.

More Like This…

Copyright ©2010-2019 AlgaeIndustryMagazine.com. All rights reserved. Permission required to reprint this article in its entirety. Must include copyright statement and live hyperlinks. Contact editorial@algaeindustrymagazine.com. A.I.M. accepts unsolicited manuscripts for consideration, and takes no responsibility for the validity of claims made in submitted editorial.

twittertopbarlinks_eventstopbarlinks_requesttopbarlinks_archives

From The A.I.M. Archives

— Refresh Page for More Choices
Globally, an increase in water pollution is pushing scientists and environmental care specialists to seek best ways of preserving and maintaining sources of safe drinking...
French researchers have been exploring the potential of algae for boosting the immune systems of animals and reducing the use of antibiotics in livestock farming. Past st...
Amy Thompson writes in Space.com that SpaceX successfully launched its 15th Space Station cargo-resupply mission on Friday, June 29; carrying a payload of experiments des...
Sophie Kevany writes in Decanter.com that a group of vineyards in France’s Bordeaux and Cognac regions are exploring whether algae can be used to prevent the fungal infec...
Algae and corals have been leaning on each other since dinosaurs roamed the earth, much longer than had been previously thought, according to new research led by scientis...
Alexander Richter writes in thinkgeoenergy.com that Israel-based Algaennovation last week signed a 15-year contract with Icelandic energy utility and operator ON Power fo...
San Diego, CA and Kailua-Kona, HI-based Cellana, Inc. has signed an Asset Purchase Agreement with Cyanotech Corporation for the sale of Cellana’s six-acre production and ...
Milenio.com reports that BiomiTech, a Mexican company, won a prestigious innovation award for its air purification system at the Contamination Expo Series 2018 held in Bi...
E.A. Crunden writes in thinkprogress.org that Florida’s first gubernatorial debate was dominated by environmental and climate issues, with an emphasis on the state’s alga...
Julianna Photopoulos writes in Horizon EU Research and Innovation magazine that UK start-up Skipping Rocks Lab aims to use natural materials extracted from plants and sea...
Mazda U.K. has announced that they are currently involved in joint research projects and studies as part of an ongoing industry-academia-government collaboration to promo...
London-based architectural and urban design firm ecoLogicStudio www.ecologicstudio.com, led by Claudia Pasquero and Marco Poletto, has unveiled Photo.Synth.Etica, a large...