[ad#PhycoBiosciences AIM Interview]

Research

Algae Can Increase Good Cholesterol, Says W.S.U. Researcher

July 11, 2012
AlgaeIndustryMagazine.com

Wayne State University researcher Smiti Gupta, Ph.D.

Wayne State University researcher Smiti Gupta, Ph.D.

Aresearcher at Detroit, Michigan’s Wayne State University has found that an extract from algae could become a key to regulating cardiovascular disease.

In a study funded by Health Enhancement Products of Bloomfield Hills, Mich., Smiti Gupta, Ph.D., assistant professor in the department of nutrition and food science in the College of Liberal Arts and Sciences, has found that dietary intake of ProAlgaZyme increased the level of high-density lipoprotein (HDL) in an animal model.

While medications for the control of high plasma cholesterol levels such as statins and numerous dietary supplements primarily function by lowering levels of low-density lipoproteins (LDL), or “bad cholesterol,” Gupta’s research explores the effects of raising levels of HDL, or “good cholesterol,” which work in part by carrying cholesterol out of the arterial wall.

Results of her study, titled “ProAlgaZyme and its Sub-fractions Increase Plasma HDL-Cholesterol via Up Regulation of ApoA1, ABCA1 and SRB1 and Inhibition of CETP in Hypercholesterolemic Hamsters,” were published recently in the Journal of Nutrition and Dietary Supplements.

“The cholesterol mechanism is crucial to heart disease,” Gupta said. “Very few agents increase good cholesterol, but we found that this algae extract does. The ratio of total to HDL cholesterol improved significantly. This result, if replicated in humans, would be consistent with a decreased risk of heart disease.”

ProAlgaZyme, a clear liquid, was administered as part of the drinking fluid over four weeks. In addition to increasing HDL levels, the group found that it also changed the expression of genes involved in the reverse cholesterol transport mechanism. And while they don’t know exactly how it will function in humans, Gupta said other research suggests a similar outcome.

“Its biological effect over time and toxic effects, if any, need to be further investigated in a long-term study in an animal model before testing its effects in humans,” she said. “But this is a step in the right direction, since increased HDL is considered an important therapeutic target for improvement of the lipid profile and thus reduction of the risk for cardiovascular disease.”

More Like This…

Go to HOME Page

Copyright ©2010-2012 AlgaeIndustryMagazine.com. All rights reserved. Permission granted to reprint this article in its entirety. Must include copyright statement and live hyperlinks. Contact editorial@algaeindustrymagazine.com. A.I.M. accepts unsolicited manuscripts for consideration, and takes no responsibility for the validity of claims made in submitted editorial.

From The A.I.M. Archives

— Refresh Page for More Choices
Bioenergy-news.com reports that Volkswagen showcased its algae biogas-powered vehicle at a biogas project based in El Torno Chiclana, a town in south-west Spain. The test...
Benedict O’Donnell writes in the EU Research and Innovation magazine, Horizon, about research being developed on seaweed as a biological, environmentally friendly, sustai...
Jason Smith reports for undercurrentnews that Kentucky-based Alltech is willing to invest in overseas algae production plants closer to its feed customers if demand for i...
Nicolas Sainte-Foie writes for Labiotech.eu about French startup Algopack manufacturing bio-based plastics made from brown algae. Founded by Rémy Lucas in 2010 and manage...
Fraunhofer-Gesellschaft reports in Science Daily that two algae species survived 16 months on the exterior of the International Space Station (ISS) despite extreme temper...
Aquaculture is the fastest-growing segment in the feed industry. According to the 2017 Alltech Global Feed Survey, the aquaculture industry experienced a 12 percent incre...
The University of Kentucky (UK) Center for Applied Energy Research’s (CAER) Biofuels and Environmental Catalysis Group has received a $1.2 million U.S. Department of Ener...
Qualitas Health, an algae-based health and nutrition company headquartered in Texas, has announced a long term, strategic partnership with commercial crop producer Green ...
Algatech has announced the opening of Algatech Inc., a New York City-based subsidiary created to serve the North American market. The company has appointed Ken Seguine to...
David Erickson writes in the (Montana) Missoulian that Clearas Water Recovery, a Missoula tech company formed eight years ago, has developed a patented process to use alg...
Sex self-destruction represents a fascinating new scientific mystery that includes climate chaos, ghost forests, temperature spikes, fierce storms, colossal nutrient coll...
The United States Department of Energy (DOE) announced that the University of New England was awarded a three-year, nationally competitive research grant for $1,321,039 f...